PLAC8 participates in the prognosis regulation of breast cancer by regulating the infiltration of immune cells in the tumor microenvironment
Objective To investigate the mechanism of Placenta-specific 8 (PLAC8) in the tumor microenvironment (TME) of breast cancer. Methods Two single-cell RNA-seq datasets (GSE161529 for primary breast cancer, GSE150660 for leptomeningeal metastasis) were integrated to profile microenvironmental composition and PLAC8 expressi...