BACKGROUND
Inflammation and metabolic dysregulation are closely linked to mental disorders. This study systematically compared three metabolic-inflammatory indices-remnant cholesterol inflammatory index (RCII), neutrophil-to-high-density lipoprotein cholesterol ratio (NHR), and C-reactive protein-triglyceride-glucose i...
Predicting cellular responses to perturbation requires resolving coordinated changes across molecular layers, yet most single-cell perturbation models focus on transcriptional responses alone. Here we present MultiFlow, a coupled flow-matching framework that unifies generation and perturbation prediction of paired gene...
Plasma GDF15 is associated with a broad range of incident brain disorders and may act partly through lipid- and inflammation-related pathways, particularly HDL-C and neutrophil count.
Xin-Ru Guo, Song-Yu Wu, Zhou-Yang Sun et al.· Progress in Neuro-psychophar...· 0 citations
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