Tandem-Gated DNA Nanomachine Enables In Vivo Visualization of Mitochondrial Nickel Ions from Nickel Alloy Implants
No approach has been reported for the in vivo detection of mitochondrial nickel ions (Ni2+), despite their crucial importance for elucidating the early timing, dynamic progression, and potential intervention windows of nickel-induced mitochondrial damage. Therefore, a tandem-gated DNA nanomachine (C-12S-Zyme-tFNA) th...