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Meng-Yan Chen

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Review Open access Sep 2026

Integrated network toxicology and multiomics analyses reveal the mechanisms underlying trimethyltin chloride-induced epilepsy and the ameliorative effects of astaxanthin via NFKB1 and IL6.

Trimethyltin chloride (TMT) is a ubiquitous neurotoxic organotin pollutant that induces epilepsy, while the natural marine product astaxanthin (AST) exerts potent antioxidant, anti-inflammatory and neuroprotective effects. However, the causal molecular mechanisms of TMT-induced epilepsy and the targeted intervention me...

Ming-Ke Qin, Dao Zhou, Hao-Xu Wu et al. · 0 citations

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