Author

Meng-Ying Guan

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Review Open access Sep 2026

LIMCH1 in Cancer: A Context-Dependent Modulator Beyond the Tumor Suppressor–Oncogene Dichotomy

LIM and calponin homology domain-containing protein 1 (LIMCH1) has recently gained attention as a functionally perplexing factor in human cancers, with studies attributing both tumor-suppressive and tumor-promoting properties that defy simple categorization. Originally described as an actin-associated cytoskeletal prot...

Meng-Ying Guan, Hua Hao · International Journal of Mol... · 0 citations

Review Open access Jul 2026

CDK4/6 Inhibitors in Breast Cancer: Clinical Applications, Translational Insights, and Future Directions

This review examines the clinical development of palbociclib, ribociclib, and abemaciclib across both early-stage and metastatic settings, revealing clinically meaningful differences in efficacy that challenge the notion of a uniform class effect.

Meng-Ying Guan, Hua Hao · Cancers · 0 citations