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Meng-Yu Li

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Jul 2026

Substrate-Oriented Channel Engineering of D-Amino Acid Oxidase for Efficient L/D-Phosphinothricin Resolution: Synergies of Geometric and Electrostatic Modifications.

D-Amino acid oxidase (DAAO) catalyzes the oxidation of D-phosphinothricin (D-PPT) to produce optically pure L-PPT, but low catalytic efficiency limits its industrial application. Here, a synergistic strategy combining geometric remodeling and charge engineering was applied to enhance the oxidation activity of our previ...

Meng-Yu Li, Chen-Chen Fu, W. Zhuang et al. · 0 citations

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