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Author

Meng-Yu Li

2 papers indexed here

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Sep 2026

Substrate-pocket reshaping of an (R)-selective transaminase enables efficient asymmetric synthesis of (R)-3-amino-1-butanol.

(R)-Selective ω-transaminases are valuable biocatalysts for the synthesis of chiral amines and pharmaceutical intermediates, but their practical application is often limited by insufficient catalytic efficiency, poor operational stability and unfavorable reaction equilibrium. Here, an Actinomycete-derived (R)-selective...

Xin-Yu Lu, Feng Guo, Cao-Kai Zhu et al. · 1 citation
Sep 2026

An Enzyme from a Single P450 Monooxygenase Clade Orchestrates Six‑Electron Oxidation for Cyclopeptide Modification

This study characterizes IlaL, a cytochrome P450 monooxygenase from Streptomyces atratus, which catalyzes a six‑electron methyl‑to‑carboxylic acid conversion during the biosynthesis of the potent antimycobacterial cyclopeptide ilamycins.

Ming Peng, Qiao-Ling Wu, Ying-Ying Chen et al. · 0 citations

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