Meng-Zhen Chen

Lipid droplet organized metabolic vulnerabilities in melanoma: from the MITF low state to ferroptosis sensitization

Melanoma’s ability to progress and develop resistance to therapies are the result of both genotypic changes and substantial levels of adaptability at the phenotypic and metabolic level. One of the most clinically relevant adaptive states is the microphthalmia associated transcription factor MITF low, which has been cor...