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Mengdi Shao

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Aug 2026

Rutin targeting NOX4 alleviates sepsis-induced acute lung injury via inhibition of NET formation through the ROS/MAPK/PAD4 pathway.

Neutrophil extracellular traps (NETs) have been identified as pivotal contributors in driving excessive inflammation and organ damage during sepsis. Rutin has shown broad therapeutic potentials in inflammatory, infection, and cancer disease models. However, its role in sepsis-associated acute lung injury (ALI) has not...

Yanhui Zhu, Mengdi Shao, Qingyan Zheng et al. · 0 citations

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