Open access
Jul 2026
Oligodendroglial TANGO2 Regulates Lipid Metabolism to Control Motor Coordination.
TANGO2 deficiency disorder (TDD) is a rare genetic disease caused by mutations in the TANGO2 gene, characterized by prominent neurological symptoms. However, the pathological mechanisms underlying TANGO2 loss-of-function in neurologic symptoms remain unknown. Here, we generated constitutive and cell-type-specific Tango...
Jiewen Chen, Zhili Liu, Fengling Chen et al.
· The FASEB Journal · 0 citations