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Subacute oral toxicity of Sinopodophyllum hexandrum fruit in mice: Integrated assessment of target-organ injury and gut microbiota alteration.
ETHNOPHARMACOLOGICAL RELEVANCE Sinopodophyllum hexandrum (Royle) T.S. Ying fruit (SHF) is recorded in the Chinese Pharmacopoeia as a Tibetan medicine for regulating menstruation and promoting blood circulation. Although its pharmacological potential (e.g., anticancer, hypolipidemic) is recognized, little is known about...