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Aug 2026

SETD5 regulates leukemic initiation and infiltration in T-cell acute lymphoblastic leukemia.

It is demonstrated that SETD5 contributes to T-ALL progression by regulating transcriptional programs that contribute to leukemic cell migration and infiltration, suggesting that SETD5-associated transcriptional programs warrant further investigation as potential vulnerabilities in T-ALL.

Ming-Yue Hao, Yu-Jie Bian, Mengke Li et al. · 0 citations

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