Alisol B 23-acetate alleviates lipopolysaccharide-induced acute lung injury by targeting ANXA1 to modulate the ANXA1/FPR2-mediated MAPK/NF-κB signaling axis.
BACKGROUND Acute lung injury (ALI), a common respiratory disease with high morbidity and mortality, poses a serious public health threat. Apart from mechanical ventilation, limited safe and effective clinical therapies are available. Alisol B 23-acetate (AB23-a), one of the principal bioactive components of Rhizoma Ali...