A P450-mediated trade-off: Terpenoid metabolism comes at the cost of pest resistance in Pleurotus ostreatus.
Cytochrome P450 monooxygenases (P450s) core catalytic regulators of secondary metabolism and biotic stress defense across plants and fungi. The fungivore mite Tyrophagus putrescentiae is a major pest of cultivated mushrooms, but the molecular basis of fungal defense against this fungivore remains poorly understood. Her...