Mengwei Ye

Copper/tetrasulfide co-doped mesoporous organosilica for multimodal imaging-guided photothermal tumor stiffness modulation and synergistic chemo-chemodynamic therapy of triple-negative breast cancer.

Elevated tumor stiffness, mainly caused by dense extracellular matrix deposition, severely restricts nanodrug penetration and weakens the efficacy of combined cancer therapy for triple-negative breast cancer. Herein, we developed a copper/tetrasulfide co-doped mesoporous organosilica (CM) coated with polydopamine and l...