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Author

Mengxing Chen

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2 papers indexed here

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Open access Oct 2026

Machine learning-based predictive model for pulmonary hypertension risk stratification in chronic kidney disease: development, internal validation and temporal external validation

Among chronic kidney disease (CKD) patients referred for right heart catheterization (RHC) due to clinical suspicion of pulmonary hypertension (PH), PH is a highly prevalent complication and contributes to increased cardiac mortality. This study aimed to develop and validate a machine learning (ML)-based predicti...

Meng-Xing Chen, Yang Zhang, Li Fan et al. · 0 citations
Jul 2026

IL-33 as a component of neutrophil extracellular traps mediates contrast-induced acute kidney injury by promoting ferroptosis in tubular epithelial cells.

It is demonstrated that IL-33-enriched NETs promote renal tubular ferroptosis in CIAKI by suppressing IKKα and impairing β-catenin nuclear translocation, thereby de-repressing long chain acyl CoA synthetase 4 transcription and amplifying ferroptotic injury.

Meng-Qing Ma, Hao Zhang, Weijuan Deng et al. · 0 citations

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