Protocatechuic Acid Protects Neural Stem Cells against Cerebral Ischemia-Reperfusion Injury by Suppressing JAK2/STAT3 Signaling and Restoring Mitophagy.
BACKGROUND AND OBJECTIVES Neural stem cells (NSCs) are important for endogenous brain repair but are highly vulnerable to mitochondrial dysfunction during cerebral ischemia-reperfusion injury (CIRI). Preliminary bioinformatics analysis suggested that immune microenvironment remodeling and JAK/STAT signaling activation...