Triple-negative breast cancer (TNBC) is highly aggressive and lacks targeted therapies. This study investigated the anti-cancer mechanisms of sinapaldehyde (SNAH). The biological effects of SNAH were evaluated in vitro using MDA-MB-231 TNBC cells. Cellular responses, including autophagy, mitochondrial function, apoptos...
H. Kumarasinghe, Ducdat Le, Ji-Hyang Kim et al.· International Journal of Mol...· 0 citations
These findings provide mechanistic evidence supporting the traditional medicinal use of P. pyrifolia and establish a theoretical framework to develop phytopharmaceuticals for inflammatory diseases.
Ducdat Le, D. Rhyu, Mi-Na Lee· Antioxidants· 0 citations
A plasma-derived protein fraction (MG-1) was partially purified from the hemolymph of the Pacific oyster, Magallana gigas, and its potential modulatory effects on lipopolysaccharide (LPS)-induced inflammatory responses were evaluated in HT-29 intestinal epithelial cells. SDS-PAGE analysis revealed two major protein ban...
Seung-Yub Song, Sung-Ho Lee, Dae-Hun Park et al.· International Journal of Bio...· 0 citations
Integrated network pharmacology and molecular docking analyses suggested that the active glycosides may exert their anti-inflammatory effects through the modulation of multiple inflammation-related targets and signaling pathways, providing a plausible mechanistic basis for their observed anti-inflammatory activity.
H. Q. Nguyen, Hien Thi Tran, L. T. Thao et al.· Carbohydrate Research· 0 citations
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