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Author

Mi-Young Son

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Open access Sep 2026

A self-crosslinkable, adhesive intestine-derived extracellular matrix hydrogel enhances organoid retention and restores intestinal barrier integrity

Disruption of the intestinal barrier impairs essential functions of the gastrointestinal tract and triggers severe inflammation. Accordingly, transplantation of intestinal organoids restores the integrity of the injured intestinal barrier by promoting regeneration. However, the dynamic mucosal microenvironment of the i...

Ye-Seul Kim, S. Han, S. An et al. · 0 citations
Open access Sep 2026

Breast cancer-associated fibroblast-derived exosomal miR-1290 promotes triple-negative breast cancer cell proliferation

It is demonstrated that treatment with the mTOR inhibitor rapamycin and the FDA-approved rapamycin analog everolimus effectively suppressed miR-1290-induced TNBC cell proliferation, suggesting a potential therapeutic strategy for TNBC.

Jinkwon Lee, Taesang Son, Gyeonghwa Kim et al. · 0 citations
Open access Jul 2026

Pharmacological Blockade of NMUR2 Suppresses Glioma Growth by Inhibiting STAT5-Mediated Transcription of Cell Cycle-associated Genes

These findings define a previously unrecognized NMUR2/Gαq/Ca²⁺/STAT5/PIM1-FOXM1 signaling axis in glioma and support pharmacological inhibition of NMUR2 as a potential therapeutic strategy.

Yuna Roh, Taesang Son, Tae-Hee Han et al. · 0 citations
Open access Jul 2026

Alu-mediated SPAST deletion impairs golgi zinc transport and reveals a druggable vulnerability

These findings identify a primate-specific cascade linking Alu-mediated genomic rearrangements to zinc dyshomeostasis and Golgi pathology and suggest that dysregulation of the ZnT6–Golgi axis may represent a vulnerability and therapeutic target in structural variant–driven neurodegeneration and possibly in a subset of...

Youngsun Lee, Onju Ham, Hana Lee et al. · 0 citations

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