Transmembrane Protein Disulfide Isomerase TMX3 Potentiates Platelet Aggregation and Arterial Thrombosis in Mice.
BACKGROUND Several members of the PDI (protein disulfide isomerase) family have been shown to regulate platelet function and thrombosis. TMX3 (thioredoxin-related transmembrane protein 3), the sole transmembrane member of the PDI family containing catalytically inactive thioredoxin-like domains, has been implicated in...