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Miaomiao Jiang

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Open access Sep 2026

Disrupting Mitochondrial Homeostasis via TBC1D15 Protein

Highlights What are the main findings? Subcellular inter-organelle trafficking of TBC1D15, rather than its whole-cell protein abundance, is identified as the critical switch governing mitochondria–lysosome homeostasis and mitochondrial quality control. CCCP and high-dose AuNPs modulate TBC1D15 through two divergent reg...

Peng-Fei Qiang, Yan Li, Shuang Liang et al. · 0 citations
Jul 2026

Spatiotemporal multiomics uncover tumor ecosystem dynamics during metastatic colonization.

A residual population of quiescent Phgdhhigh DTCs that survived initial innate immune clearance and became transiently enriched in micrometastases are identified, providing insights into the development of micrometastasis-targeting regimens.

Yun-Fan Sun, Y. Zhong, Shang Liu et al. · 0 citations

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