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Author

Michael C. Kelly

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Open access Jul 2026

Alterations in chromatin organization promote totipotent-like features in a DPPA2/DUX-dependent manner

It is shown that disruption of chromatin organization by degron-mediated CTCF and/or WAPL depletion promotes totipotent-like conversion through the DPPA2/DUX axis, accompanied by changes in chromatin accessibility and nucleolar integrity.

Grace Carey, Maria Vega-Sendino, Desiree Tillo et al. · 2 citations

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