Michael P. Fischbein

Single-Cell Proteomics Uncovers Cell-Specific Proteins in Vascular Health and Marfan Syndrome Disease

Background: The vascular system is the largest organ in the body and underlies most chronic diseases, yet the molecular mechanisms that govern its plasticity remain poorly defined. Methods: We applied single-cell proteomics for the first time in vascular disease, integrating it with single-cell transcriptomics to map p...