Open access
Aug 2026
ACBD5 as a Master Tether of Peroxisomes: Integrating Organelle Contact Sites, Lipid Sensing, and Cellular Homeostasis
An expanded view of ACBD5 function is proposed, suggesting that it acts as a peroxisomal “master tether” that integrates intracellular organisation with metabolic and homeostatic regulation by linking lipid sensing and metabolism to the formation and regulation of membrane contact sites.
Michael Schrader, P. Kim, Ruth E. Carmichael
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