Author

Michael T. Eadon

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Open access Sep 2026

spaGFM is a scalable graph foundation model for spatial transcriptomics analyses

Foundation models offer a promising paradigm for modeling spatial transcriptomics, but capturing tissue context over cellular graphs makes training at scale challenging. We introduce spaGFM, a graph foundation model that serializes cellular neighborhoods through random walks to generate transformer-compatible represent...

Yu Zhong, Fei He, Xiao-Jie Jin et al. · Research Square · 0 citations

Open access Sep 2026

A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease.

Epigenetic aging is a hallmark of chronic diseases. While such epigenetic changes can arise following tissue injury, the cell types most affected remain largely unknown. Here we built a cross-species single-cell multiomics atlas of DNA methylation, chromatin accessibility and transcription profiles from healthy, injure...

Hyeonsoo Jeong, B. Lake, D. Dinh et al. · Nature Aging · 0 citations

#human-computer interacti... Preprint Sep 2026

Evaluating Usability in Biomedical Visualization: Rethinking Heuristic Evaluation for Spatial Omics and Multidisciplinary Research Platforms

Three specialized heuristics are proposed that help developers manage complexity, provide contextual support, and improve accessibility for multidisciplinary research teams: Active Parameter Transparency, Point-of-Use Guidance, and Phased Feature Disclosure.

Yulia A. Levites Strekalova, Rachel Liu Galvin, Jessica Ray et al. · 0 citations