Michael Wang

Mitochondrial ROS-induced metabolic alterations differentially regulate ferroptosis vulnerability of hepatocytes.

Ferroptosis is an iron-catalyzed lipid peroxidation (LP)-dependent cell death that mediates the development of many diseases, including liver injury. Compelling evidence has suggested a crucial role of mitochondrial reactive oxygen species (mtROS) in the induction of ferroptosis, but the underlying mechanism remains po...