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Author

Michael Way

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Open access Sep 2026

Distinct Arp2/3 isocomplexes drive axonal actin ring assembly and integrity

The actin-related protein 2/3 (Arp2/3) complex is a central nucleator of branched actin filaments, essential for numerous cellular processes. Using superresolution imaging, we demonstrate that Arp2/3 is a component of the membrane periodic skeleton (MPS)—a highly ordered actin ring-spectrin lattice in the submembrane a...

A. R. Costa, Teresa Lopes, Luís P. Rodrigues et al. · 0 citations
Open access Sep 2026

The actomyosin cortex controls t-tubule remodeling in skeletal muscle

It is shown that the actomyosin cortex beneath the plasma membrane, regulated by Arp2/3 complexes containing Arpc5, acts as a gatekeeper for the membrane availability during t-tubule growth.

A. R. Pereira, Silvia Di Francescantonio, Ana da Rosa Soares et al. · 0 citations
Open access Jul 2026

In situ structure of the poxvirus portal complex.

Poxviruses are a family of large, complex double-stranded DNA viruses that includes human pathogens such as variola-the cause of smallpox-and monkeypox. Recent outbreaks of mpox underscore the need for a better understanding of poxvirus biology1,2. Poxvirus assembly is a conserved process that involves the formation of...

T. Calcraft, Miguel Hernández-González, Michael Way et al. · 0 citations

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