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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Michael Y. He

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Sep 2026

A 2-in-1 Strategy for the Discovery of Compact HDAC8 Protac Degraders

A “2-in-1” PROTAC design strategy for developing more compact HDAC8 degraders by integrating the CRBN-recruiting ligand into the capping group of an HDAC8 warhead, thereby enabling a single structural motif to engage both HDAC8 and CRBN.

Yi Liu, Nikee Awasthee, Yufeng Xiao et al. · 0 citations

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