Open access
Oct 2026
Heterogeneity and Intercellular Coupling Prevent Sinus Arrest in Rabbit Sinoatrial Node Model
Abstract The sinoatrial node (SAN) is the primary pacemaker of the heart, initiating each regular heartbeat through the spontaneous activity of specialized pacemaker cells. Its automaticity is governed by a tightly regulated interplay between ionic membrane currents and intracellular calcium cycling and is highly sensi...
Michele Terren, Moritz Linder, E. Ricci et al.
· Current Directions in Biomed... · 0 citations