Open access
Sep 2026
Slow calcium removal contributes to impaired lusitropic response to β-adrenergic stimulation in HFpEF mice.
Heart failure with preserved ejection fraction (HFpEF) accounts for over half of heart failure cases, yet its underlying mechanisms remain incompletely understood and effective therapies are lacking. Diastolic dysfunction, a hallmark of HFpEF, may arise from impaired active myocardial relaxation, but the contribution o...
T. Zawadzki, Diana S. Usai, Sif G. Kaad et al.
· Journal of Physiology · 0 citations