Author

Miguel A. R. B. Castanho

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Review Open access Aug 2026

Linker Design in Antibody-Drug Conjugates: Balancing Stability and Drug Release

Mechanistic insights increasingly show that linker–payload properties govern catabolite permeability and intratumoral distribution, particularly in antigen-heterogeneous settings, particularly in antigen-heterogeneous settings.

Sara N. Albino, Margarida M. Domingos, T. Pacheco et al. · Pharmaceutics · 2 citations