Review
Open access
Sep 2026
Sarcopenia as a manifestation of systemic energetic failure with ageing.
Sarcopenia remains underdiagnosed and undertreated, partly because it continues to be mainly conceptualised as a disorder intrinsic to skeletal muscle. Although current definitions incorporate muscle strength and physical performance, they are not intended to explain the integrated physiological processes that underlie...
Luigi Ferrucci, S. Donegà, A. Picca et al.
· The Lancet Healthy Longevity · 0 citations