In situ structure of the poxvirus portal complex.
Poxviruses are a family of large, complex double-stranded DNA viruses that includes human pathogens such as variola-the cause of smallpox-and monkeypox. Recent outbreaks of mpox underscore the need for a better understanding of poxvirus biology1,2. Poxvirus assembly is a conserved process that involves the formation of...