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Author

Mikaela Koutrouli

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Open access Sep 2026

Lifespan single-cell transcriptomic atlas of the human prefrontal cortex

A single-nucleus transcriptomic atlas spanning the human lifespan is used to show that the dorsolateral prefrontal cortex exhibits non-linear, cell-type-specific transcriptional trajectories characterized by dynamic remodelling during development, relative stability in midlife and selective molecular reactivation in la...

Hui Yang, Tereza Clarence, Madeline R. Scott et al. · 4 citations
Open access Sep 2026

Single-cell atlas of transcriptomic vulnerability across brain disorders

A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.

Donghoon Lee, Mikaela Koutrouli, Nicolas Y. Masse et al. · 8 citations
Open access Jul 2026

Spatialproteomics: an interoperable toolbox for analyzing highly multiplexed fluorescence image data

This work demonstrates an end-to-end analysis from raw images to statistical characterization of how cell type composition and spatial distribution vary across indolent and aggressive lymphomas and presents a Python-based toolbox that supports end-to-end analysis of highly multiplexed imaging data.

Matthias Meyer-Bender, Harald Vöhringer, C. Schniederjohann et al. · 1 citation

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