Milagros Prendes

Induced epileptic seizures in larval zebrafish reveal a synaptic modulation associated with the post-ictal state

Data show that inhibitory drive is strengthened after seizure termination, giving rise to a post-ictal state similar to that defined in humans, a potential target for pharmacological interventions that may mitigate neurological deficits in epilepsy when the seizures themselves cannot be prevented.