As a complex airway inflammatory disease, the pathogenesis of asthma is closely associated with dynamic changes in the lung microbiome and immune regulation. Asthmatic patients with distinct inflammatory phenotypes exhibit significant alterations in the diversity and dominant microbiota of their lung microbiome, partic...
Sanguo Ren, Han-Le Li, Zeyu Dong et al.· Frontiers in Immunology· 1 citation
Influenza A virus (IAV) utilizes multiple strategies to antagonize type I interferon (IFN-I)-mediated antiviral responses to enhance its propagation within the host. Nonstructural protein 2 (NS2) is a component of the viral particle participating in the nuclear export of viral ribonucleoprotein complexes (vRNPs). How...
Xiao-Tian Yang, Jun-Nan Shi, Xin-Yu Li et al.· Virology Journal· 0 citations
Tumor-associated macrophages (TAMs) are abundant and functionally diverse components of the lung tumor microenvironment (TME) and are associated with therapeutic response and resistance in non-small cell lung cancer (NSCLC). Durable responses to immune checkpoint inhibitors (ICIs) and targeted therapies remain limited,...
Xiao-Long Wang, Zi-Heng Jiang, Qian-Qian Lu et al.· Frontiers in Oncology· 0 citations
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