Author

Min-Ho Ku

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Open access Aug 2026

Pseudotime-conditioned diffusion models for imputing time-series single-cell data

This work proposes the first pseudotime-conditioned diffusion-based imputation framework for time-series scRNA-seq data, consisting of two trajectory-aware models: pseudotime-conditioned conditional score-based diffusion imputation (P-CSDI) and pseudotime-conditioned hybrid-noise CSDI (PH-CSDI).

Graham Bishop, Min-Ho Ku, Daniel Lee et al. · Bioinformatics Advances · 0 citations