PEDV Nsp8 alanine-53 promotes viral replication in a partially DTX3L-dependent manner
Porcine epidemic diarrhea virus (PEDV) employs multiple strategies to interact with the host and promote its replication, with nonstructural proteins playing critical roles; however, the underlying mechanisms remain largely unclear. In this study, we found that PEDV infection significantly downregulated DTX3L expressio...