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Author

Min Wang

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Sep 2026

Repurposing GS-441524 to inhibit biofilm formation and virulence of Bacillus cereus

Abstract Bacillus cereus is a resilient foodborne pathogen, with biofilm formation and virulence regulated by quorum sensing (QS). This study evaluates GS-441524, the active metabolite of remdesivir, as an anti-virulence agent against B. cereus. At sub-inhibitory concentrations, GS-441524 dose-dependently reduced prote...

Kai-Zhong Xu, Di Meng, Lu-Jun Yin et al. · 0 citations
Case report Open access Aug 2026

Chronic Melioidosis Presenting with Pneumonia, Empyema, and Splenic Abscess

Clinicians should consider chronic melioidosis in patients with pneumonia and parapneumonic pleural effusion accompanied by splenic abscesses, particularly in patients with diabetes mellitus from endemic areas, particularly in patients with diabetes mellitus from endemic areas.

Yamei Zheng, Xiaozhou Yao, Min Wang et al. · 0 citations
Jul 2026

Transcriptomic Insights into Casein-Driven Adaptive Evolution of Burkholderia thailandensis: Implications for Biofilm Formation and Antibiotic Susceptibility.

It is demonstrated that casein-driven evolution selects for social 'cheaters' that conserve energy by downregulating costly virulence determinants, revealing a fundamental virulence-fitness trade-off.

Kai-Zhong Xu, Lu-Jun Yin, Zhi-Wen Ding et al. · 0 citations

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