Open access
Oct 2026
Interleukin-4 Genetic Polymorphisms Predict Susceptibility to Childhood Acute Lymphoblastic Leukemia
Background/Aim: Interleukin-4 (IL-4) is a key T-helper 2 cytokine involved in immune regulation, allergic responses, and hematological malignancies. Although aberrant IL-4 expression has been implicated in acute lymphoblastic leukemia (ALL), the contribution of IL-4 genetic polymorphisms to childhood ALL susceptibility...
Chao Chen, Jen-Sheng Pei, Wei-Ching Chien et al.
· Anticancer Research · 0 citations