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Open access Sep 2026

The Same, but Different: Shared Hallmarks and Divergent Drivers in Adult, Pediatric and Canine Glioma

Malignant gliomas are the most common primary brain tumors, with dismal outcomes. Pet dogs have been proposed as a valuable model for studying gliomas. Here, we compare spontaneously occurring gliomas from adult and pediatric human and canine patients, focusing on the tumor microenvironment (TME) and the canonical path...

R. Bentley, S. Utturkar, Harish Kothandaraman et al. · 0 citations

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