Jul 2026
MAPT-derived circTau6 induces tau pathogenesis and neurodegeneration by encoding Tau variants.
Findings identify circTau6/cTau4R as a post-transcriptional mechanism that modulates tauopathy and partially recapitulated molecular signatures observed in human tauopathic brains.
Guangtong Jiang, Dan-Ni Wang, Lin Shao et al.
· Molecular Psychiatry · 0 citations