Mingchi Ma

Circulating tumor DNA-based minimal residual disease-guided adjuvant therapy in solid tumors: Current evidence, clinical trial frameworks, and future directions.

The postoperative management of resectable solid tumors depends on clinicopathological risk stratification. However, these static criteria often fail to identify occult minimal residual disease (MRD), resulting in suboptimal adjuvant treatment characterized by either overtreatment or undertreatment. Circulating tumor D...

Global burden and inequality of childhood kidney cancer (1990–2050): a systematic analysis for the global burden of disease study 2021

Predicting Intratumoral Heterogeneity and Stratifying Prognostic Risk in Gastric Cancer Using a Histology-Based Pathomics-Deep Learning Fusion Model.

Intratumoral heterogeneity (ITH) is a fundamental driver of clonal evolution and therapeutic resistance in gastric cancer (GC). However, the clinical assessment of ITH remains limited by the high cost and technical complexity of multi-region and single-cell sequencing. This study aimed to develop a pathomics-deep learn...