Open access
Sep 2026
Aspirin suppresses cytoprotective autophagy and colorectal tumorigenesis through HSP90AA1 K410 acetylation-mediated ULK1 ubiquitination and degradation
Colorectal cancer (CRC) remains a significant global health challenge with high recurrence rates despite therapeutic advancements, underscoring the urgency for innovative therapeutic strategies. Clinical trials have demonstrated that aspirin treatment correlates with reduced cancer incidence, recurrence, metastasis,...
Fang Wang, Yu-Huan Zhang, Xing-Chen Dai et al.
· Cell Death & Disease · 0 citations