Despite the transformative advances that have been made in cancer immunotherapy, primary and acquired resistance remain prevalent, limiting durable clinical benefits. Mechanistic studies on immunotherapeutic resistance have largely focused on genetic, transcriptional, signaling, and metabolic programs within tumor and...
Yuan Xue, Wei Gao, Kun-Kang Deng et al.· Pharmacological Research· 0 citations
Glioblastoma (GBM) remains one of the most lethal cancers, with recurrence in nearly all patients despite standard therapy. However, the biological mechanisms governing recurrence remain incompletely understood. Increasing evidence suggests that recurrence is driven not only by tumor-intrinsic resistance, but also by d...
Jian-Yu Lu, Rou-Xi Song, Wei Gao et al.· Biochimica et biophysica act...· 0 citations
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