Author

Ming-Ju Hsieh

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Open access Sep 2026

Jaceidin Inhibits Proliferation and Promotes Apoptosis in Oral Squamous Cell Carcinoma Cells by Regulating Survivin and AKT/ERK Signaling Pathways

Oral squamous cell carcinoma (OSCC) remains a clinically challenging malignancy because of recurrence, treatment resistance, and limited therapeutic efficacy in advanced disease. This study investigated the anticancer effects and molecular mechanisms of jaceidin (JAC), a naturally occurring flavonoid derivative, in hum...

Ming-Ju Hsieh, Hsin-Yu Ho, Chia-Chieh Lin et al. · International Journal of Mol... · 0 citations

Open access Aug 2026

Analysis of single nucleotide polymorphism of SYNE1 gene in Oral squamous cell carcinoma

It is suggested that SYNE1 rs2295190 may be associated with OSCC progression rather than overall disease susceptibility, particularly in the context of betel quid exposure.

Ming-Ju Hsieh, Hsin-Yu Ho, Yu-Sheng Lo et al. · Journal of Cancer · 0 citations

Review Open access Aug 2026

The Role of Mitochondrial ROS in Neoplastic Transformations, Progression and Therapeutic Targeting

This review summarizes the major sources and regulation of mtROS, their involvement in cancer-associated signaling pathways, mitochondrial calcium dynamics, metabolic adaptations, and resistance to anticancer therapies, and discusses current and emerging mitochondrial- targeting strategies aimed at exploiting mtROS sig...

B. Velmurugan, Shu-Hui Lin, Chih-Yang Huang et al. · Oncology Research · 0 citations