Ming-Jun Zhu

Recent advances in research on the multifactorial mechanisms underlying paclitaxel resistance and translational intervention strategies

Paclitaxel (PTX) is a well-established chemotherapeutic agent that is widely used in clinical practice. It exerts its antitumor activity primarily by stabilizing microtubules and disrupting mitosis, and it is currently used in the treatment of various solid tumors, including ovarian, breast, non-small cell lung, and ga...