Open access
Sep 2026
Alpk1 activates JAK2/STAT3 signaling to enhance M1-microglial activation in epileptic rats.
BACKGROUND Epilepsy is a chronic brain disorder characterized by recurrent, highly synchronous abnormal neuronal discharges leading to cerebral dysfunction. This study investigates the role of alpha kinase 1 (ALPK1), a pattern recognition receptor, in epilepsy. METHODS ALPK1 expression and distribution were analyzed...
Jing Chen, Hong-Yin-Long Cui, Ming-Kui Zhao et al.
· Brain Research Bulletin · 0 citations