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Sep 2026

A Transformer-Based Deep Learning Model for Prediction of Temozolomide Resistance in Glioblastoma Using Pretreatment MRI Images.

OBJECTIVE Glioblastoma (GBM) is a lethal tumor where temozolomide (TMZ) chemotherapy often faces resistance. We develop a deep learning model based on a Vision Transformer (ViT) architecture for pretreatment prediction of TMZ resistance. METHODS We retrospectively enrolled 314 GBM patients across four centers between...

Cai-Qiang Xue, Sheng-Lin Li, Yu-Feng Li et al. · 0 citations
Oct 2026

Unraveling the DUSP5/ERK/OXPHOS Axis: miR-92b-3p's Role in Lung Adenocarcinoma Progression and Metastasis.

microRNA dysregulation plays a pivotal role in the tumorigenesis and metastasis of lung adenocarcinoma (LUAD). Building upon preliminary studies that identified miR-92b-3p as a potential diagnostic biomarker, this research elucidates its oncogenic mechanisms. Through the integration of cell functional assays, xenograft...

Jia-Miao Weng, Yan Lin, Ming Liu et al. · 0 citations

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