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Review Open access Oct 2026

Immune–chondrocyte ligand–receptor axes in osteoarthritis: microenvironmental control of inflammation, matrix remodeling, and chondrocyte fate

Osteoarthritis (OA) is increasingly recognized as a whole-joint disease shaped by chronic low-grade inflammation, matrix damage, mechanical stress, and failed tissue repair. Beyond the traditional view of cartilage wear, emerging evidence indicates that immune–chondrocyte ligand–receptor (LR) communication plays a cent...

Ming Liu, Chen-Guang Zhong, Ling-Yue Yuan et al. · 0 citations

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